Professional Information

Dr. M. Siva Selva Kumar M.Pharm., Ph.D. Designation : Associate Professor

Pharmacy (Pharmaceutical Analysis), Ph.D.
Year Designation Place
January 2016 to till date Associate professor PSG IMS&R, Coimbatore
September 2011 to December 2015 Associate professor PSG College of Pharmacy, Coimbatore
September 2008 to August 2011 Senior Research Officer (DMPK department) Glenmark Pharmaceutical Ltd., Mumbai
July 2007 to August 2008 Research Scientist (DMPK department) Jubilant Biosys Ltd., Bangalore
June 2004 to June 2007 Senior Analyst (BA & BE Studies) Sitec Labs Pvt. Ltd., Cipla Mumbai.
  • Method development and validation of drugs in the biological matrix (Blood, Plasma, Brain, CSF etc.,) using HPLC, UPLC and LC-MS/MS.
  • Analysis of pre-clinical and clinical (TDM) samples by using HPLC, UPLC and LC-MS/MS.
  • Analysis of neurotransmitters in brain tissues using HPLC-ECD detector.
  • Preparation and review of the method of analysis, study protocol, and analytical summary report.
  • Design the study plan and study protocol for Pre-clinical and clinical studies.
  • To impart technical training to the student.
  • To write and revise SOPs as per need and ensure implementation.
  • Behera D, Pattem R, SivaSelvaKumar M, Gudi GS. Utility of a column-switching LC/MS/MS method in cytochrome P450 inhibition assays using human liver microsomes. Drug Metabol Drug Interact. 2013;28(3):177-85.
  • Peter Christoper GV, Vijaya Raghavan C, Siddharth K, Siva Selva Kumar M, Hari Prasad R. Formulation and optimization of coated PLGA - Zidovudine nanoparticles using factorial design and in vitro in vivo evaluations to determine brain targeting efficiency. Saudi Pharm J. 2014 Apr;22(2):133-40.
  • Siram K, Chellan VR, Natarajan T, Krishnamoorthy B, Mohamed Ebrahim HR, Karanam V, Siva Selva Kumar M, Ranganathan HP. Solid lipid nanoparticles of diethylcarbamazine citrate for enhanced delivery to the lymphatics: in vitro and in vivo evaluation. Expert Opin Drug Deliv. 2014.
  • Balakumar KrishnamoorthyS. M. Habibur RahmanN. TamilselvanR. HariprasadM. Rajkumar, Siva Selva Kumar M, K. VamshikrishnaMarslin GregoryChellan Vijayaraghava. Design, formulation, in vitro, in vivo, and pharmacokinetic evaluation of nisoldipine-loaded self-nanoemulsifying drug delivery system. Journal of Nanoparticle Research. 2015; 17: 34.
  • Siva Selva Kumar M, Ramanathan M. Concurrent determination of olanzapine, risperidone and 9-hydroxyrisperidone in human plasma by ultra performance liquid chromatography with diode array detection method: application to pharmacokinetic study. Biomed Chromatogr. 2016 Feb;30(2):263-8.
  • Rajan RK, Siva Selva Kumar M, Balaji B. Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism. Pharm Biol. 2017 Dec;55(1):242-251.
  • Ramanujam N, Sivaselvakumar M, Ramalingam S. Fast and parallel determination of PCB 77 and PCB 180 in plasma using ultra performance liquid chromatography with diode array detection: A pharmacokinetic study in Swiss albino mouse. Biomed Chromatogr. 2017 Nov;31(11).
  • Jeyalakshmi D, Bhuvaneshwari S, Murugesan PR, Sivaselvakumar M. Comparative Study on Estimation of Acenocoumarol Levels in Blood in Patients with Extremes and Normal INR Values after Valve Replacement Surgery. Journal of Clinical & Diagnostic Research. 2018 Oct 1;12(10).
  • Member of the Indian Pharmaceutical Association
  • General course on Intellectual property (WIPO Academy)